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Top mental health startups 2026: AI, pediatric & enterprise care

mental health startups

The psychological result of the pandemic has enormously expanded the need for digital mental health services and triggered a rise of interest in businesses that provide them. 

Digital mental health is no longer only limited to psychological therapy or medication management. Lots of companies–both startups and more established companies–now offer psychedelic therapy, help for children and adolescents, executive coaching, and specific treatment for conditions like insomnia, anxiety, and ADHD. 

There is no lack of applications and services creating innovative ways to make mental health care more accessible, affordable, and easier to use. Here are ten of our top choices for mental health startups to follow.

While some of the next startups reconceived new tools, products, or services, others have improved existing technologies in new ways. If you want to promote mental health startup, it is much easier with the PRNEWS.IO service. It’s a company that already has a significant list of media contacts to create, publish and distribute press releases and other content, so important to introduce all mental health startups’ plans and attract investors and publicity.

The best mental health startups

Abridge

Abridge is a category-defining ambient AI scribe that automates clinical documentation for mental health providers. Its native integration with Epic EHR has made it foundational infrastructure across large healthcare systems. By eliminating administrative overhead, Abridge allows therapists to focus entirely on patient care while maintaining clinical and billing accuracy. Two $100M+ funding rounds in 2025 cemented its role as a core AI layer in behavioral healthcare.

Upheal

Upheal is purpose-built for psychiatric and therapy workflows, automating progress notes, intake summaries, and session analytics. Unlike generic medical scribes, it is optimized for therapeutic language, modalities, and outcomes tracking. In 2025, Upheal raised a $10M Series A, reflecting strong demand from private practices and group clinics. The platform directly addresses clinician burnout while increasing billable capacity.

Eleos Health

Eleos Health functions as a real-time clinical co-pilot for therapists during sessions. It uses AI to surface insights such as patient sentiment, risk signals, and adherence to evidence-based frameworks like CBT. Positioned as analytics infrastructure rather than a consumer app, Eleos supports quality assurance and payer reporting. By 2025, it had become an essential tool for outcomes-driven mental healthcare.

Wysa

Wysa is a clinically validated AI mental health chatbot that bridges the gap between self-help and professional care. In 2025, it expanded into wearable integrations, enabling personalized interventions based on physiological signals such as HRV. The platform is widely used by employers and healthcare systems as a scalable first-line support tool. Its empathetic AI coaching model has been validated across multiple clinical studies.

Woebot

Woebot is one of the few FDA-listed AI mental health platforms, trusted by healthcare systems for population-scale emotional support. Built on CBT principles, it delivers structured therapeutic interactions through conversational AI. By 2025, Woebot was deployed across hospitals, insurers, and universities. Its regulatory credibility differentiates it from consumer-grade mental wellness apps.

Slingshot AI

Slingshot AI represents the frontier of “agentic” mental health systems—AI that can reason, adapt, and proactively intervene. After raising a $53M Series A in 2025, the company focused on autonomous therapeutic agents capable of adjusting care strategies in real time. Its technology is designed to augment clinicians rather than replace them. Slingshot’s approach signals a shift toward continuous, adaptive mental healthcare.

Bend Health

Bend Health specializes in pediatric and adolescent mental health through a collaborative care model. The platform integrates therapy, psychiatry, and parent coaching, emphasizing early intervention and measurement-based care. By coordinating families, clinicians, and primary care providers, Bend reduces escalation into crisis-level care. It has become a preferred solution for youth mental health in 2025.

Cartwheel

Cartwheel embeds mental health services directly into K–12 school systems. Its model provides therapy, crisis response, and care coordination within the school community. In 2025, Cartwheel raised a $35M Series B, reflecting growing demand for school-centered mental health infrastructure. The company addresses access gaps where traditional healthcare systems fall short.

Manatee

Manatee delivers family-centered mental healthcare combining child therapy with structured parent coaching. Its virtual model emphasizes engagement and gamification, achieving high participation and rapid symptom reduction. In 2025, Manatee reported an 87% reduction in symptoms within six weeks for active users. The platform demonstrates the effectiveness of family-integrated digital care.

Equip

Equip is a leader in virtual treatment for eating disorders, one of the highest-risk psychiatric conditions. Its care model uses a five-person multidisciplinary team to deliver evidence-based family treatment at scale. Backed by payers and insurers, Equip addresses a high-cost, high-acuity population. Its growth reflects investor preference for condition-specific platforms with measurable outcomes.

Author Health

Author Health focuses on seniors with serious mental illness, a population historically underserved by digital health. The platform blends virtual psychiatric care with community-based support and Medicare-aligned operations. By addressing both clinical and social needs, Author Health fills a critical gap in behavioral healthcare. It represents the next wave of age-specific mental health innovation.

Ellipsis Health

Ellipsis Health uses vocal biomarkers to objectively assess depression, anxiety, and stress through speech analysis. Its AI detects subtle vocal patterns that correlate with mental health conditions. In 2025, the platform moved from research into clinical workflows, supporting early detection and triage. Ellipsis exemplifies the shift toward measurable, data-driven mental health diagnostics.

Kintsugi Voice

Kintsugi Voice analyzes short speech samples to identify signs of depression and emotional distress. Integrated into healthcare intake and triage systems, it enables early intervention at scale. The technology is designed to support clinicians with objective emotional data before therapy begins. By 2025, it was increasingly used in health system workflows.

Flow Neuroscience

Flow Neuroscience offers a non-invasive, medication-free depression treatment using transcranial direct current stimulation (tDCS). Its consumer-friendly headset is paired with app-based behavioral therapy. Clinically validated in Europe and expanding globally, Flow reflects growing interest in neurotechnology for mental health. The platform bridges digital therapeutics and neuroscience.

HelloBetter

HelloBetter is a leader in Germany’s “apps on prescription” ecosystem, offering reimbursable digital therapeutics for depression, anxiety, and insomnia. Its programs are evidence-based and certified under the DiGA framework. In 2025, the company raised €6M to expand into new European markets. HelloBetter demonstrates how regulatory alignment accelerates mental health innovation.

Nabla

Nabla is a conversational AI assistant designed to function as a real-time clinical co-pilot for healthcare professionals, including mental health providers. Its platform combines ambient documentation, clinical reasoning support, and conversational intelligence to reduce the cognitive and administrative burden placed on clinicians. Unlike traditional AI scribes, Nabla emphasizes dialogue-driven interaction, allowing clinicians to query patient context, treatment history, and documentation logic during or after sessions. By 2025, Nabla has positioned itself as a high-growth infrastructure layer within digital health, favored by organizations seeking scalable, AI-native clinical workflows rather than point solutions.

Slingshot AI

Slingshot AI represents a new generation of mental health technology built around “agentic” AI systems rather than static chatbots. The company develops advanced models that simulate therapeutic reasoning, enabling software agents to interpret patient dialogue, detect shifts in emotional state, and dynamically adjust intervention strategies. These systems are designed to proactively engage patients between clinical touchpoints, supporting continuity of care and early intervention at scale. Following its $53 million Series A in 2025, Slingshot AI emerged as a frontier player in autonomous mental healthcare, signaling a shift toward AI systems that actively participate in therapeutic processes rather than merely responding to user input.

Daybreak Health

Daybreak Health operates as a district-level mental health infrastructure partner for K–12 schools, delivering evidence-informed skill-building programs directly within educational systems. Its model emphasizes early intervention, family engagement, and coordination with school staff to address student mental health needs before they escalate into crises. By working at the district rather than individual school level, Daybreak achieves scalability while maintaining alignment with educational outcomes and community context. In 2025, the company is positioned as a critical enabler of preventative, school-based mental healthcare.

Handspring Health

Handspring Health is an evidence-based pediatric behavioral health platform focused on delivering structured therapy for children and adolescents. The company specializes in standardized, outcomes-driven care models designed to reduce long waitlists that plague pediatric mental health services. In 2025, Handspring raised $12 million to expand its operations nationally, reflecting strong demand from payers and health systems for clinically rigorous pediatric solutions. Its emphasis on fidelity to evidence-based protocols differentiates it from more generalized youth mental health platforms.

Backpack Health

Backpack Health provides a youth-focused virtual mental health platform with a strong emphasis on culturally competent care. Designed to serve diverse populations, the platform integrates therapy, care coordination, and culturally responsive engagement strategies to improve access and retention among underserved youth. Backpack Health positions itself at the intersection of equity and digital health, addressing structural barriers that often limit the effectiveness of standard virtual care models. In 2025, it stands out as a mission-driven platform aligned with broader healthcare inclusion goals.

Blackbird Health

Blackbird Health focuses on neurodevelopmental care for children with autism and ADHD through a hybrid model that combines in-person clinics with AI-supported diagnostic and care coordination tools. The company addresses one of the most critical bottlenecks in pediatric behavioral health: long delays in diagnosis and fragmented access to specialists. By integrating advanced assessment workflows with clinical teams, Blackbird accelerates diagnostic timelines while maintaining clinical rigor. In 2025, it is positioned as a scalable solution for payers and health systems seeking to close access gaps in high-demand neurodevelopmental services.

Finni Health

Finni Health delivers Applied Behavior Analysis (ABA) therapy directly into the home, supporting children with autism and related neurodevelopmental conditions. Its platform emphasizes continuity of care from diagnosis through long-term treatment, coordinating therapists, families, and care plans in a single digital environment. By moving care into the home setting, Finni Health reduces logistical barriers and improves adherence for families. In 2025, the company stands out as a technology-enabled provider in one of the most clinically intensive and resource-constrained areas of pediatric mental health.

Amaha

Amaha, formerly InnerHour, delivers a comprehensive mental health ecosystem built around a 360-degree bio-psycho-social care model. The platform integrates psychiatry, therapy, self-care tools, and lifestyle interventions, recognizing the interdependence of mental, physical, and social health factors. Operating at scale in India, Amaha addresses complex psychiatric conditions rather than mild wellness needs, making it a critical provider in a market with significant provider shortages. By 2025, it has emerged as one of the strongest examples of whole-person mental healthcare in emerging markets.

Spring Health

Spring Health is a data-driven enterprise mental health platform focused on delivering personalized care pathways for employees and their families. Using advanced matching algorithms, the platform connects users to therapists, coaches, and digital interventions tailored to clinical needs, preferences, and outcomes data. Its emphasis on measurable ROI—such as reduced absenteeism and improved productivity—has made it a benchmark solution for large employers. In 2025, Spring Health is widely regarded as a category leader in the evolution of “EAP 2.0.”

Lyra Health

Lyra Health provides clinical-grade mental healthcare to enterprise clients, combining evidence-based therapy, psychiatry, and digital care navigation. The platform is known for its rigorous provider network, outcomes tracking, and close integration with employer health benefits. Rather than offering generic wellness content, Lyra focuses on high-quality, structured mental health treatment with demonstrated clinical impact. By 2025, it is one of the most widely adopted mental health solutions among Fortune 500 employers.

Tess

Tess is a conversational AI platform engineered for enterprise and public-sector deployment, delivering scalable, real-time mental health support. Its AI adapts to the emotional state and cultural context of users, enabling dynamic engagement across large populations. By 2025, Tess has positioned itself as a leading solution for organizations seeking automated, clinically-informed interventions at scale.

Ginger

Ginger, now part of Headspace Health, integrates therapy, coaching, and digital tools to create personalized mental health programs for employees. The platform emphasizes measurable workplace outcomes, such as reduced stress and improved productivity, combining human support with data-driven insights. In 2025, Ginger is recognized as a benchmark for enterprise mental health solutions that deliver quantifiable ROI.

Sword Health

Sword Health, originally a digital physical therapy provider, expanded into mental health through its “Mind” program, which applies AI to address the psychological dimensions of chronic pain. The platform combines behavioral health interventions with data-driven care pathways, bridging physical and mental health treatment. Its $40 million funding round in 2025 highlights investor confidence in convergent care models.

Tia

Tia is a women’s health platform integrating teletherapy and mental health screenings with primary care services, including acupuncture and wellness support. By combining mental and physical care, Tia provides a holistic approach tailored to the unique needs of women across life transitions. In 2025, it exemplifies the market trend toward “whole-person” healthcare solutions.

Floreo

Floreo employs VR modules to support social and emotional skill development in neurodiverse youth, including children with autism and ADHD. Its clinically validated programs provide immersive exposure therapy, anxiety management, and social training. By 2025, Floreo is recognized as a leader in the adoption of VR for evidence-based pediatric behavioral interventions.

Paradromics

Paradromics develops high-bandwidth brain–computer interfaces (BCIs) that enable real-time streaming and analysis of neural data. While broader than mental health alone, its technology has direct applications in cognitive and behavioral interventions. In 2025, Paradromics is positioned at the frontier of neurotechnology, bridging neuroscience, AI, and therapeutic potential.

Neuralink

Neuralink focuses on implantable BCIs designed to restore cognitive and motor function in neurological disorders, with implications for psychiatric care. Its $600 million Series E funding in 2025 underscores its ambition to transform treatment for both physical and mental health conditions. Neuralink’s roadmap positions it as a strategic player in the next generation of neurotechnology-enabled mental health interventions.

Unmind

Unmind is a B2B mental health platform for enterprise clients, featuring its proprietary AI agent, Nova, which delivers personalized guidance and insights to employees. The platform combines therapy, coaching, and digital interventions to enhance workplace well-being while providing employers with actionable analytics. In 2025, Unmind stands out as a leader in AI-driven, outcomes-focused corporate mental health solutions in Europe.

Healios

Healios provides virtual psychiatric assessments and therapy for children and adolescents, operating in close collaboration with the UK’s National Health Service (NHS). Its platform enables scalable access to clinically supervised mental health care for youth, addressing gaps in traditional service delivery. By 2025, Healios is recognized as a benchmark in evidence-based, telepsychiatry solutions for pediatric populations in the UK.

Naluri

Naluri integrates mental health support into broader digital health and wellness ecosystems across Southeast Asia. The platform combines health coaching, behavioral interventions, and digital therapeutics to deliver holistic well-being programs for users and enterprises. By 2025, Naluri exemplifies regionally tailored, data-driven approaches to workplace and population mental health.

1to1help

1to1help is India’s leading Employee Assistance Program (EAP) provider, delivering counseling services in 14 languages to over 800 companies. Its platform combines self-care resources, therapy, and organizational reporting tools to support large-scale corporate mental health needs. In 2025, it is the primary reference point for enterprise mental health solutions in India, emphasizing accessibility and cultural competence.

Moka.care

Moka.care is a France-based platform focused on women’s mental health during life transitions, offering counseling, coaching, and community support. Its mission-driven approach addresses the unique psychological and emotional challenges faced during maternity, menopause, and career changes. Having raised $16 million in Series A funding in 2025, Moka.care is scaling its services nationally and preparing for broader European expansion.

Serenis Health

Serenis Health specializes in neurocognitive and mental health diagnostics in Italy, leveraging advanced assessment tools to detect and monitor cognitive and psychiatric conditions. Its platform provides objective, measurement-based insights that support early intervention and personalized treatment planning. By 2025, Serenis Health is recognized as a clinical leader in diagnostic innovation within the European mental health landscape.

Bottom line: mental health startups

Many people do not know about these mental health startups and new technologies concentrating on mental healthcare software development. We can say that these startups are changing millions of affected people’s lives, and people are getting positive results with their new technologies. 

If you know more interesting mental health apps, leave a comment with them. You never know whose life it will improve.

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