Telehealth has changed how people access hormone replacement therapy, but not all startups deliver the same level of medical follow-through. Some platforms feel like a guided clinic experience, while others look more like a subscription service with labs and renewals. Therefore, the smartest way to compare options is to focus on the patient journey: who they treat, how they decide eligibility, and how they monitor changes.
Below are the top five startups that offer HRT-related services. Each overview focuses on what the company does, how the process usually works, and what to check before you commit.
1) Beyoung Health
Beyoung Health is an online clinic that supports hormone-related care and other medication-based programs with licensed provider oversight. As a result, the experience is presented as a structured clinical pathway rather than a quick checkout. You can choose the service you’re looking for upfront, which keeps the intake and follow-ups focused.
Main Services:
- BHRT for menopause and women’s hormone concerns
- testosterone replacement therapy for men who may need TRT after clinical assessment
- medically supervised weight loss programs
How it works: First, you complete a medical questionnaire and arrange lab tests. Next, a medical expert reviews your information and checks eligibility. After that, you book a one-on-one video consultation to review results, discuss goals, and agree on a plan. Finally, if the clinician approves treatment, the prescription is sent to the pharmacy you choose.
After you start, follow-ups and repeat testing help keep care on track. Therefore, the plan can be adjusted based on symptoms and lab results.
What to keep in mind: Hormone therapy tends to work best when the basics stay consistent. So, compare how the clinic handles follow-up timing, renewals, and questions between appointments.
2) Hone Health
Hone Health offers care tracks for both men and women, and it frames its service around hormone health and longevity-style support. Still, testosterone therapy is a major theme, especially on the men’s side. So, it fits best as TRT-forward rather than TRT-only.
How it generally works: The platform presents care as an ongoing program that starts with labs and continues through periodic reassessment. In practice, that model can appeal to patients who want repeated check-ins and a predictable renewal rhythm, especially when symptoms or biomarkers change.
What to keep in mind: Because this platform includes more than TRT, confirm what your plan actually covers, and what is considered an add-on. Also, if you are comparing TRT options specifically, ask how often labs repeat and how dose changes are handled. That monitoring detail often matters more than branding.
3) Evernow
Evernow focuses on menopause care and presents hormone therapy as one option within a broader symptom plan. As a result, it reads less like a “hormones-only” shop and more like a menopause support service with ongoing adjustments.
How it works: Evernow describes clinician-guided HRT options and ongoing care through membership-style plans. It also lists a range of hormone formats and notes that medication costs can be separate and may run through a local pharmacy, depending on coverage.
What to keep in mind: Menopause symptoms can overlap with sleep problems, thyroid issues, and mood changes. Therefore, it’s worth checking how the platform handles follow-ups when symptoms do not respond as expected, and what happens when a patient needs a different approach.
4) Gennev
Gennev positions itself around virtual menopause support from perimenopause through post-menopause. It emphasizes symptom relief and evidence-based treatment, which makes the offering feel like a structured menopause clinic rather than a single-purpose HRT vendor.
How it works: Gennev describes reviewing health history and symptoms to determine whether a patient is a candidate for hormonal medications, including hormone replacement therapy. So, the decision point is framed as clinical fit, not just preference.
What to keep in mind: If you want HRT, check how the service schedules follow-ups and how it tracks symptom response over time. Also confirm what support looks like when symptoms are complex, since menopause often affects more than one system at once.
5) FOLX Health
FOLX Health offers gender-affirming hormone therapy, and it uses HRT language in its education materials. As a result, it can be a strong fit for patients who want hormone care designed around LGBTQIA+ needs, communication preferences, and longer-term support.
How it works: The platform describes getting started with gender-affirming hormone therapy through a guided telehealth pathway. Then, ongoing care and adjustments can continue through the service, which matters because hormone goals and dosing can evolve.
What to keep in mind: Licensing and lab access vary by region. Therefore, it’s important to confirm provider coverage where you live and how monitoring is handled across follow-ups. That clarity can prevent delays later.
A Quick Way To Compare These Startups Without Getting Lost
If you want a simple filter that works across all five, focus on three questions:
- How do they decide eligibility? A serious platform explains the clinical “yes” and the clinical “no.”
- What does monitoring look like? Labs and follow-ups should feel routine, not optional.
- How clear are costs and renewals? Membership, labs, and medication can be packaged differently, so clarity beats low headline pricing.
When those answers are easy to find, the rest becomes a preference decision. And when they are hard to find, that’s useful information too.
