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Top 5 Mental Health Startups in the U.S.

Mental health startups are becoming increasingly relevant in our society as they draw attention to arguably one of the most veiled taboo topics in our society: Mental Health. Since the first Mental-Health Startups emerged in the area of the United States of America and in most cases can be used from Germany as well, we have created a list of the best Mental-Health Startups in the USA.

  • Lyra Health
  • Pear Therapeutics
  • Modern Health
  • Sanity & Self
  • Calm

The best 5 mental health startups in the USA

Lyra Health

Founders: Bob Kocher, David Ebersman, Dena Bravata

Lyra Health is one of the few mental-health startups creating a frictionless experience for members, providers, and employers* to revolutionize mental health care (especially in the U.S.). The company uses modern technology and relevant data to bring companies and their employees* closer together through providers and mental health treatments. Lyra Health was originally founded in San Francisco, California in 2015 by Bob Kocher, David Ebersman and Dena Bravata. Referred to as this startup, it is an advocate for all-inclusive mental health care. The company’s focus is primarily on helping employees with urgent mental health treatment needs. They also specifically support working parents during their children’s back-to-school time. Accordingly, the startup’s services are divided into family care, preventive care, moderate & complex needs, and global support.

Pear Therapeutics

Founder: Corey M. McCann

Mental health startup Pear Therapeutics is a digital company that offers digital therapies for a wide range of serious mental illnesses. The startup’s treatments are particularly applicable to the categories of addiction, schizophrenia, psychosomatic pain, post-traumatic stress disorder, anxiety, depression and sleep disorders. In this context, the therapeutic platform combines, among other things, pharmaceutical preparations with user-friendly, customizable and scientifically validated software applications. In addition, Pear Therapeutics’ patented approach is aimed at achieving optimized outcomes for individual patients and using smarter engagement and tracking tools for physicians. In addition, solutions for appropriate payers in particular are intended to be solved in a cost-effective manner.

Modern Health

Founders: Alyson Watson, Erica Johnson

Modern Health is another startup dedicated to the mental well-being of workers*. The digital platform is specifically targeted at innovative companies that want to prevent employee burnout and turnover. Founders Alyson Watson and Erica Johnson launched the company in 2017 and have been advocating for mentally healthy leadership in companies ever since. For example, the website advertises that Modern Health anticipates the mental health needs of its clients*. The company aims to make value-based care for users* easily accessible, personalized, culturally centered, and most importantly, actionable for employers*. Modern Health is available as an app in the app store.

Sanity & Self

Founder: Meng Li

Self-care is a relevant aspect of a mentally healthy life and is too rarely considered a priority. That’s what the founder of mental health startup Sanity & Self thought. Sanity & Self is a platform that helps users* receive well-deserved self-care through a guided wellness app. The app is specifically designed to bring about a reduction in stress through small, bite-sized audio content. Accordingly, experts in sleep, meditation, fitness, nutrition, beauty and breathing are used to help users of the program practice healthy self-care. In addition, the app is specifically designed for women to create a safe, trusting environment.


Founders: Alex Tew & Michael Acton Smith

Calm is one of the most well-known mental health apps. The company works to bring amazing benefits of meditation to a world drilled on performance, business, and economic growth. This mental-health startup forms an online portal that offers busy and information-overloaded workers* a way to relieve stress in a healthy way. Founders Alex Tew and Michael Acton Smith created the startup in May 2012 and were named iPhone App of the Year by Apple in 2017. When using the app, users can individually decide which goal they would like to achieve through the app. Consequently, the categories offered include these goals: Sleep Quality Improvement, Stress and Anxiety Reduction, Focus Optimization, and Self-Optimization. The app can be downloaded from the app store for daily use.



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